The International Institute for Sustainable Laboratories (I2SL) serves a broad coalition of lab owners, facility managers, architects, builders, engineers, vendors, and other professionals interested in sustainable design, system optimization, green labs, and decarbonization. In addition to the nearly 40 technical sessions and roundtables on these key topics, the 2024 I2SL Annual Conference will kick off with an Opening Plenary session spotlighting some of the organization’s hottest topics and priorities for the coming years, demonstrating how they are addressing decarbonization and sustainability in four key ways at the local, national, and international level: